Endocrine Abstracts

Background: The aim of this study was to assess health-related quality of life (HRQoL) of patients living in cities and towns with different population in the Russian Federation (RF) using EQ-5D questionnaire, to calculate health utility index (QALY) and cost-utility ratio (CUR).Methods: One of the goals of the multicenter, observational, epidemiologic study FORSIGHT-DM2 was to evaluate HRQoL using the EQ-5D Questionnaire. The study included more than 20...

Introduction: An atypical manifestation of disease combined with inconsistent results of examination, long history of multiple past health care services without effect requires to consider factitious disorders.Case report: A 46 year-old woman was suffering from episodes of severe hypokalemia (K+ 1.9 - 3.4 mmol/l (ref. 3.5-5.1 mmol/l) and hypertensive crises up to 240/145 mm Hg for 4 years. She stated that there was no clear provoking factor for these epi...

Introduction: Primary hyperparathyroidism (PHPT) is commonly the most early manifestation of multiple endocrine neoplasia syndrome type 1 (MEN1), but it can also occur in young patients without any inherited disorders. The aim of our study was to compare the clinical characteristics of PHPT in young patients with MEN1 syndrome and with sporadic disease.Patients and Methods: The study included 72 patients with MEN-1 associated PHPT and 168 patients with s...

Introduction: Chronic hypoparathyroidism is a rare disease, which usually treated with active forms of vitamin D and oral calcium. Supplementation with native vitamin D can be useful both for achieving "non-skeletal" effects of vitamin D and for a more stable serum calcium profile.Aim: The aim of this study was to estimate the daily serum calcium and 24-hour urine calcium levels in patients with chronic hypoparathyroidism depending on different 2...